The film was a commercial success, grossing over $746 million worldwide, making it one of the highest-grossing films of 2012. The film's success can be attributed to its broad appeal, with something for everyone to enjoy.

Madagascar 3: Europe's Most Wanted has left a lasting impact on the world of animation. The film's success helped to cement the Madagascar franchise as a beloved and iconic series, with a loyal fan base. The film's 3D presentation also helped to push the boundaries of what was possible in animated filmmaking.

Madagascar 3: Europe's Most Wanted received generally positive reviews from critics and audiences alike. The film holds a 79% approval rating on Rotten Tomatoes, with many praising its humor, animation, and 3D presentation.